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2022 18th Annual Resident Research Day and Otolaryngology Symposium

Presented by University Hospitals Ear, Nose & Throat Institute

Friday, June 3, 2022 | 7:30 am - 4:30 pm
Tinkham Veale University Center
11038 Bellflower Road
Cleveland, OH 44106

Learning Objectives

After attending this program, participants will be able to:

  • Define the role of TMC proteins within the inner ear
  • Identify the organization of the cochlea potential targets to preserve hearing
  • Discover the latest advances regarding Meniere's disease, Usher Syndrome Type III and Enlarged Vestibular Aqueduct including diagnosis and treatment
  • List new drug targets for the treatment of head and neck squamous cell carcinoma, including chemotherapy options when immunotherapy fails
  • Recognize the different prognosis based on HPV+ versus HPV negative oropharyngeal cancer as well as the prognosis effects based on referral patterns
  • Name different techniques of aerosol generating procedures
  • Describe the difference in loss of smell and taste related to the Covid pandemic
  • Outline the indications, techniques and outcomes of tracheal transplantation

Continuing Education

Physicians / Category 1
Case Western Reserve University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Case Western Reserve University School of Medicine designates this live activity for a maximum of 6.5 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses and Physician Assistants
Non-physician attendance credit is provided to non-physicians who participate in activities that were designated for AMA PRA Category 1 Credit(s)TM. The American Nurses Credentialing Center (ANCC) and the American Academy of Physician Assistants (AAPA) accept certificates of participation for educational activities certified for AMA PRA Category 1 Credit(s)TM from organizations accredited by the Accreditation Council for Continuing Medical Education or a recognized state medical society. It is suggested that learners check with their state licensing board to ensure it accepts reciprocity with AMA PRA Category 1 Credit™ for re-licensure.

Registration

This is a free conference but registration is requestedClick here for conference registration.

PROGRAM AGENDA

7:30 am | Breakfast

7:45 am | Welcome
Nicole Maronian, MD, FACS

7:55 am | Introduction to the Morning Program
Kumar Alagramam, PhD

HEARING RESEARCH

8:00 am | The Role of TMC Proteins in Lateral Line
Brian McDermott, PhD

8:10 am | Intermediate Cells of Dual Embryonic Origin Ingress in the Lateral Wall of the Cochlea Following a Basal to Apical Gradient
Martin Basch, PhD

8:20 am | Targeting Mitochondrial Calcium Uptake in Cochlear Cells to Protect Hearing
Ruben Stepanyan, PhD

8:30 am | Understanding the role of stress hormones in Meniere’s Disease
Justine Renauld, PhD

HEAD AND NECK CANCER RESEARCH

8:40 am | Repurposing Fenofibrate as an Anti-Cancer Agent for HNSCC
Wendi O’Neill, DDS, MS

8:50 am | CRISPR/Cas9 Kinome Screen Identifies Novel Druggable Target for HPV- HNSCC
Katherine Chatfield-Reed, PhD

9:00 am | Definitive Treatment Choice on the Prognosis of Complete Responders with p16+ and p16- OPSCC
R. Grant Muller, MD, PGY4 Resident

9:10 am | Cisplatin/Paclitaxel Doublet to Manage Pembrolizumab-Refractory HNSCC
Kyunghee Burkitt, DO, PhD

9:20 am | Extra Nodal Extension in Oral Cavity Cancer
Claudia Cabrera, MD, MS

9:30 am | Prognostic Significance of Referral Patterns and Time Trends in Head and Neck Cancer Management
Divya Balchander, BS

9:40 am | BREAK
Visit with sponsors, review posters

LARYNGOLOGY RESEARCH

9:50 am | Understanding Aerosol Generating Procedures: Background Orient Schlieren and Other Techniques
N. Scott Howard, MD & Bryan Schmidt, PhD

RHINOLOGY RESEARCH

10:05 am | Smell and Taste Disturbance in the COVID Era: Diagnostic and Therapeutic Considerations
Brian D’Anza, MD

PEDIATRIC RESEARCH

10:20 am | Hearing Loss due to Enlarged Vestibular Aqueduct: From Diagnosis to Prognosis
Todd Otteson, MD

FACIAL PLASTIC RESEARCH
10:35 am | Investigating the Relationship of COVID-19 and Facial Paralysis
Cyrus Rabbani, MD

DR. JAMES E ARNOLD LECTURE SERIES

11:00 am | Introduction to Dr. James E. Arnold Lecture Presenter
Rod Rezaee, MD, FACS

Tracheal Transplantation – from Bench to Bedside
Eric Genden, MD, MHCA, FACS
The Isidore Friesner Endowed Professor and Chairman
The Department of Otolaryngology - Head and Neck Surgery
The Icahn School of Medicine at Mount Sinai

12:00 pm | LUNCH
Visit with sponsors, review posters

CWRU/UH ENT ALUMNI LECTURE SERIES

12:30 pm | Introduction
Rod Rezaee, MD, FACS

The Business of Medicine in 2022
Cliff Megerian, MD, FACS
Chief Executive Officer; Jane and Henry Meyer Chief Executive Officer Distinguished Chair
University Hospitals Health System
Professor of Otolaryngology - Heck and Neck Surgery
Case Western Reserve University  School of Medicine

CASE BASED LEARNING

1:00 pm | Complex Airway Panel
Moderator: N. Scott Howard, MD
Panelist: Shawn Li, MD, Eric Genden, MD, Luis Argote-Green, MD, Benjamin Young, MD

1:30 pm | Head and Neck Cancer Panel
Moderator: Nicole Fowler, MD
Panelists: Pierre Lavertu, MD, Ted Teknos, MD, Jason Thuener, MD, Shawn Li, MD, Eric Genden, MD, Danielle Scarola, MD

2:00 pm | BREAK
Please visit our sponsors and review posters

2:15 pm | Pediatric ENT Panel - Airway Management for Infants with Pierre Robin Sequence
Moderator: Matthew Gropler, MD
Panelists: Todd Otteson, MD, Jay Shah, MD, Tekin Baglam, MD

2:45 pm | Rhinology Panel: Nasal Drainage to Revisions, Management of Commonly Seen Rhinologic Problems
Moderator: Brian D’Anza, MD
Panelists: W. Colby Brown, MD, John Gerka, MD, Nipun Chhabra, MD, Courtney McAvinew, CNP

3:30 pm | Closing Remarks
Rod Rezaee, MD & Nicole Maronian, MD, FACS

4:00 pm | Adjourn

Evaluation and CME Credit Certificate

Conference Evaluation and CME Credit Claim Instructions:

Step 1: Evaluation UH ENT Resident Research Day & Symposium - be sure to record the credit claim number (Activity ID) at the end of the evaluation.
Step 2: Go to https://cwru.cloud-cme.com
Step 3: Click "Sign In" on the top left, and sign in using your email address and password.
Step 4: Click the "My CME" button on the top right-hand side of the screen.
Step 5: Click the "Claim Credit" button.
Step 6: Enter the Event ID you recorded after completing your evaluation and click the “Submit ID” button.
Step 7: Complete any additional questions or fields.
Step 8: Once your credits are recorded, you will then be taken back to My CME. Go to Evaluations & Certificates. Your certificate will be there and available for printing.

You have 7 days to claim credit via the mobile app; 30 days via desktop.
For step by step instructions, click here: https://bit.ly/CMECreditClaimInstructions

For further information or questions, contact the CME Program
10524 Euclid Avenue
Cleveland, OH 44106-6026
Tel: 216-983-1239 Fax: 216-844-8133
Email: medcme@case.edu
https://cwru.cloud-cme.com

Conference Faculty

KEYNOTE SPEAKER

Eric M. Genden, MD

Eric M. Genden, MD MHCA FACS
The Isidore Friesner Endowed Professor and Chairman
The Department of Otolaryngology - Head and Neck Surgery
Professor of Neurosurgery
Professor of Immunology
The Recanati-Miller Transplant Institute
The Icahn School of Medicine at Mount Sinai
Dr. Genden, faculty for this educational event, has no relevant financial relationship(s) with
Ineligible companies to disclose

CWRU/UH ALUMNI SPEAKER
Cliff Megerian, MD FACS
Chief Executive Officer; Jane and Henry Meyer Chief Executive Officer Distinguished Chair
University Hospitals Health System
Professor, Otolaryngology - Head and Neck Surgery
Case Western Reserve University School of Medicine
Dr. Megerian, faculty for this educational event, has no relevant financial relationship(s) with
Ineligible companies to disclose.

ACTIVITY DIRECTOR
Rod Rezaee, MD, FACS
Director, Head and Neck Surgical Oncology and Reconstruction
Director, Head and Neck Surgery Fellowship
UH Ear, Nose & Throat Institute / UH Seidman Cancer Center
Associate Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Rezaee has received honoraria from Zimmer/Biomet. The relevant financial relationship listed has been mitigated.

CO-ACTIVITY DIRECTOR
Nicole Fowler, MD, FACS
Associate Director, Head and Neck Surgery Fellowship
UH Ear, Nose & Throat Institute / UH Seidman Cancer Center
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Fowler, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose. 

PLANNING COMMITTEE
Kumar Alagramam, PhD
Director, Research
Anthony J. Maniglia Chair, Research & Education
Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Alagramam, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Nicole Maronian, MD, FACS
Richard W. and Patricia R. Pogue Leadership Chair in Otolaryngology – HNS
Director, UH Ear,Nose & Throat Institute
Distinguished Senior Surgeon
Julius W. McCall Associate Professor and Chair
Department of Otolaryngology – Head and Neck Surgery
Case Western Reserve University School of Medicine
Dr. Maronian, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Quintin Pan, PhD
Deputy Director, Research
Lester E. Coleman Jr. Chair, Cancer Research
UH Seidman Cancer Center
Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Pan, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Karen Walsh
Program Coordinator
UH Ear,Nose & Throat Institute
Ms. Walsh, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

ADDITIONAL SPEAKERS

Luis Argote-Green, MD
UH Thoracic & Esophageal Surgery
Assistant Professor, Surgery
Case Western Reserve University School of Medicine
Dr. Argote-Green, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Divya Balchander, BS
UH Clinical Research Fellow
Department of Otolaryngology
Drexel University College of Medicine, Class of 2023
Dr. Balchander, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Martin L. Basch, PhD
UH Ear, Nose & Throat Institute
Assistant Professor
Case Western Reserve University School of Medicine
Dr. Basch, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Tekin Baglam, MD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Baglam, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

W. Colby Brown, MD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Brown, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Kyunghee Burkitt, DO, PhD
Assistant Professor, Medical Oncology
Case Western Reserve University School of Medicine
Dr. Burkitt, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Claudia Cabrera Aviles, MD, MS
Clinical Research Fellow
UH ENT Institute
Dr. Cabrera Aviles, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Katherine Chatfield-Reed, PhD
UH Ear,Nose & Throat Institute
Postdoctoral Research Associate
Case Western Reserve University School of Medicine
Dr. Chatfield-Reed, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Nipun Chhabra, MD, FARS
Chief of Otolaryngology, VA Northeast Ohio Healthcare System
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Chhabra, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Brian D’Anza, MD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. D’Anza and his spouse owns controlling interest in and intellectual property rights to SmartDocMD. The relevant financial relationship listed has been mitigated.

John Gerka Stuyt, MD
UH Ear, Nose & Throat Institute
Assistant Professor
Case Western Reserve University School of Medicine
Dr. Gerka Stuyt, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Matthew Gropler, MD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Gropler, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

N. Scott Howard, MD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Howard, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Pierre Lavertu, MD, FACS
UH Ear, Nose & Throat Institute / UH Seidman Cancer Center
Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Lavertu, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Shawn Li, MD
UH Ear, Nose & Throat Institute / UH Seidman Cancer Center
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Li, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Courtney McAvinew, CNP
UH Ear, Nose & Throat Institute
Ms. McAvinew, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Brian McDermott, PhD
UH Ear, Nose & Throat Institute
Associate Professor
Case Western Reserve University School of Medicine
Dr. McDermott, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Sarah Mowry, MD
Residency Program Director
UH Ear, Nose & Throat Institute
Associate Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Mowry listed a conflict. The relevant financial relationship listed has been mitigated.

Wendi O’Neill, DDS, MS
UH Ear, Nose & Throat Institute
Research Scientist
Ms. O’Neill, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Todd Otteson, MD, MPH, FACS ,FAAP
Dean, Blackwell McKinley Society
Assistant Dean for Student Affairs
Chief, Pediatric Otolaryngology, Rainbow Babies and Children's Hospital
James Arnold, MD and Nancy and Tom Seitz Chair in Pediatric Otolaryngology
Associate Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Otteson, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Cyrus Rabbani, MD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Rabbani, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Justine Renauld, PhD
UH Ear, Nose & Throat Institute
Postdoctoral Research Associate
Case Western Reserve University School of Medicine
Dr. Renauld, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Alejandro Rivas, MD
Richard W. and Patricia R. Pogue Chair in Auditory Surgery and Hearing Sciences
Division Chief, Otology & Neurotology
Director, Cochlear Implant Program
UH Ear, Nose & Throat Institute
Professor, Otolaryngology-Head & Neck Surgery
Professor of Neurological Surgery
Case Western Reserve University School of Medicine
Dr. Rivas, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Danielle Scarola, MD
Head and Neck Fellow
UH Ear, Nose & Throat Institute
Clinical Instructor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Scarola, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Bryan Schmidt, PhD
Assistant Professor, Mechanical & Aerospace Engineering
Case Western Reserve University School of Engineering
Dr. Schmidt, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Jay Shah, MD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Shah, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Ruben Stepanyan, PhD
UH Ear, Nose & Throat Institute
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Stepanyan, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Akina Tamaki, MD
UH Ear, Nose & Throat Institute / UH Seidman Cancer Center
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Tamaki, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Leonidas Tapias, MD
UH Thoracic & Esophageal Surgery
Assistant Professor, Surgery
Case Western Reserve University School of Medicine
Dr. Tapias, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Theodoros Teknos, MD
President, UH Seidman Cancer Center
Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Teknos, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Jason Thuener, MD
UH Ear, Nose & Throat Institute / UH Seidman Cancer Center
Assistant Professor, Otolaryngology
Case Western Reserve University School of Medicine
Dr. Thuener, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

Benjamin Young, MD
Medical Director, Bronchoscopy
Pulmonary & Critical Care Medicine
University Hospitals Cleveland Medical Center
Associate Professor, Medicine
Case Western Reserve University School of Medicine
Dr. Young, faculty for this educational event, has no relevant financial relationship(s) with ineligible companies to disclose.

RESIDENT PRESENTERS
R. Grant Muller, MD, PGY4 Resident
Benjamin Johnson, MD, PGY4 Resident
Drs. Miller & Johnson, residents for this educational event, have no relevant financial relationship(s) with ineligible companies to disclose.

2022 James E Arnold MD Lectureship Presenter

Eric M. Genden, MD, MHCA, FACS
The Isidore Friesner Endowed Professor and Chairman
The Department of Otolaryngology-Head and Neck Surgery
Professor of Neurosurgery & Immunology
The Recanati-Miller Transplant Institute
The Icahn School of Medicine at Mount Sinai

A member of the Icahn School of Medicine at Mount Sinai faculty since 1988, Dr. Genden is an internationally recognized expert and innovator in the management of head and neck cancer, microvascular reconstruction of the head and neck, and transplantation. He is the Dr. Isidore Friesner Endowed Professor and System Chairman of the Department of Otolaryngology – Head and Neck Surgery and a Professor of Neurosurgery and Immunology. His many leadership roles at Mount Sinai include Senior Associate Dean for Clinical Affairs at the Icahn School of Medicine at Mount Sinai. Dr Genden plays a leadership role with the Mount Sinai Doctors Faculty Practice and he is a Senior Vice-President for Ambulatory Surgery Development.

As the Director of the Head, Neck and Thyroid Cancer Center at The Mount Sinai Hospital, Dr. Genden directs the clinical program and oversees clinical trials conducted at the NCI funded cancer center. He is also co-investigator on more than a 12 clinical trials. In addition to his clinical endeavors, Dr. Genden oversees a National Institutes of Health-funded basic science laboratory that studies the transplantation immune biology of the trachea. Dr. Genden recently performed the first human tracheal transplantation.

A thought leader in his field, Dr. Genden is a prolific author of original peer-reviewed reports including over 250 peer-reviewed manuscripts and six text books. He is an editor and reviewer for numerous journals, lecturing nationally and internationally on his work. Dr. Genden is a founding fellow of the International Academy of Oral Oncology, and past president of the New York Head and Neck Society. His many honors include a Distinguished Service Award from the American Academy of Otolaryngology-Head and Neck Surgery and the prestigious Jacobi Medallion from Icahn School of Medicine at Mount Sinai.

Dr. Genden graduated from Columbia University with a Bachelors in Medicine and Economics. He earned his medical degree with a distinction in research from the Mount Sinai School of Medicine. He completed a residency in otolaryngology-head and neck surgery at Washington University and Barnes-Jewish Hospital in St. Louis, and fellowship training in head and neck oncology and microvascular surgery at The Mount Sinai Hospital. Dr. Genden earned a Master’s degree in health care administration at the Harvard T.H. Chan School of Public Health.

James Arnold, MD FACS

James Arnold, MD FACS | Professor Emeritus
The Ear, Nose & Throat Institute at University Hospitals Cleveland Medical Center is proud to present the endowed James E Arnold MD lectureship as part of our annual ENT Symposium named in honor of his lasting contributions to our field of and enduring impact on the Department of Otolaryngology-Head and Neck surgery.

As an internationally renowned pediatric otolaryngologist, Dr. Arnold was recognized for his unwavering commitment to excellence in ENT care at University Hospitals where he was a member of the Department from its inception in 1987 to his retirement in 2017. He served as Division Director of Pediatric Otolaryngology, Program Director and Department Chairman. During that time, he was instrumental in the growth of his department, faculty recruitment, and in the education and training of innumerable students and residents. As an exemplary teacher, an astute clinician and a trusted colleague and friend, we are proud to recognize him for his contributions through this annual keynote lecture series.

Disclosure Policy

As an organization accredited by the ACCME, the Case Western Reserve University School of Medicine CME Program requires that the content of CME activities and related materials provide balance, independence, objectivity, and scientific rigor. All faculty, planners, and others in a position to control continuing medical education content are required to disclose all financial relationships with ineligible companies within the past 24 months regardless of the amount and their view of the relevance of the relationship to the education. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. Faculty (authors, presenters, speakers) are encouraged to provide a balanced view of therapeutic options by utilizing either generic names or other options available when utilizing trade names to ensure impartiality.

The Case Western Reserve University School of Medicine CME Program has implemented a mechanism to identify and resolve all conflicts of interest prior to the activity. The intent of this policy is to identify potential conflicts of interest so participants can form their own judgments with full disclosure of the facts. Participants are asked to evaluate whether the speaker’s outside interests reflect a possible bias in the planning or presentation of the activity.

Symposium Exhibit Acknowledgments

Exhibits provided by:

  • Checkpoint Surgical
  • Cook Medical
  • HB Surgical
  • Intersect ENT
  • KLS Martin
  • Medtronic
  • Stryker
  • Zimmer-Biomet 

We gratefully acknowledge their support and hope you will visit their representatives’ displays during a break in the meeting.

Acceptance of funding in support of this program does not constitute endorsement of any product or manufacturer.