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UH Digestive Health Institute – January 2018

Fabio Cominelli, MD, PhD

Chief Scientific Officer, UH Digestive Health Institute; Chief, Division of Gastroenterology & Liver Disease, UH Case Medical Center; Hermann Menges Jr. Chair and Professor of Medicine, Case Western Reserve University School of Medicine


Cores and Clinical Component

Within the center are three core laboratories and an administrative core with a clinical component:

The Biorepository Core provides a high-quality, cost-effective and efficient system to provide investigators with samples of serum, DNA, tissue and cells to investigate mechanisms of digestive inflammatory and metabolic diseases. The Biorepository Core procures, provides and stores DNA, serum and biopsy and surgical tissues from patients with gastrointestinal and liver diseases, as well as normal controls, for use in Institutional Research Board-approved research. The core also provides clinical and demographic classification of tissue and DNA samples and distributes tissue, cells and clinical specimens for investigators to use in their digestive and liver disease-related research. In addition, the Biorepository Core provides expertise in the isolation