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UH Case Medical Center's Dr. Daniel I. Simon Recognized with American College of Cardiology Top Honor

News Release

Date: March 8, 2016

Contact: Mike Ferrari, Department of Marketing & Communications

Phone: 216-844-7239

Daniel I. Simon, MDCLEVELAND — University Hospitals Case Medical Center President Daniel I. Simon, MD, FACC, has been awarded the 2016 Distinguished Scientist Award – Basic Domain by the American College of Cardiology in honor of his contributions to the cardiovascular profession. 

Dr. Simon, who also serves as President, UH Harrington Heart & Vascular Institute, will be recognized for his considerable achievements in cardiovascular medicine at the Convocation Ceremony on April 4 during the ACC’s 65th Annual Scientific Session in Chicago.

“Dr. Daniel Simon has made lasting contributions to the field of cardiovascular medicine through dedication to his patients, practice and colleagues,” said ACC President Kim Allan Williams, MD, FACC. “It is an honor to recognize Dr. Simon with the Distinguished Scientist Award and celebrate his contributions to and achievements in cardiology.”

The Distinguished Scientist Award is awarded to a Fellow of the American College of Cardiology who has made major scientific contributions to the advancement of scientific knowledge in the field of cardiovascular disease. The award is presented annually to three recipients; one each in the basic, clinical and translational domains. Sixteen total Distinguished Awards will be presented at the Annual Scientific Session.Recipients are nominated by their peers and then selected by the American College of Cardiology Awards Committee.

Dr. Simon holds the Herman K Hellerstein Chair of Cardiovascular Research at UH Case Medical Center and Case Western Reserve University School of Medicine. He is also Professor of Medicine at the School of Medicine.

An internationally recognized clinical researcher, Dr. Simon was elected into the American Society for Clinical Investigation, Association of University Cardiologists, and the Association of American Physicians. He is a recipient of the prestigious MERIT Award from the National Heart, Lung, and Blood Institute. He is a Fellow of the American College of Cardiology, the American Heart Association, and the Society of Cardiac Angiography and Interventions.

Dr. Simon’s main area of research interest is the role of inflammation in vascular injury and repair. His research is supported by grants from the National Institutes of Health, the Prentiss Foundation, the Medtronic Foundation, and the Harrington Discovery Institute at University Hospitals. Using leading-edge transcriptional profiling approaches, his laboratory has identified a novel biomarker called MRP-8/14 that predicts the risk of future heart attack and stroke.

Dr. Simon is the Co-Founder of Sujana Biotech, a start-up biotechnology company developing novel monoclonal antibodies for a range of inflammatory and vascular disorders. The company’s lead product is in the early preclinical phase of development. He is also Program Director of the Bridging the Treatment Gap for Rheumatic Heart Disease in Sub-Saharan Africa: A Uganda – Case Western Reserve University supported by the Medtronic Foundation.

He is an active interventional cardiologist and continues to play a leading role in national and international clinical trials investigating new devices, anti-thrombotic drugs, and regenerative medicine/adult stem cell therapies. He has been recognized in Best Doctor’s in America and U.S. News Top Doctors. Dr. Simon is the official cardiovascular health care physician of the NFL Cleveland Browns. He has published extensively in peer-reviewed basic science and clinical journals. Dr. Simon has served on the editorial boards of Circulation and Journal American College Cardiology and was recently appointed to the editorial board of JAMA Cardiology.

After earning his medical degree from Harvard Medical School, he completed his internal medicine residency and cardiovascular medicine fellowship at Brigham and Women’s Hospital and interventional cardiology training at Beth Israel Hospital, Harvard Medical School. He joined the faculty of Brigham and Women’s Hospital where he rose through the ranks to Associate Professor of Medicine, Harvard Medical School.

“Dr. Daniel I. Simon has made multiple contributions to basic and translational research through serial groundbreaking discoveries.” said Dr. Peter Libby, Dr. Simon’s mentor and renowned scientist and cardiologist from Harvard Medical School. “Important clinical problems have always inspired Dr. Simon’s laboratory studies. He has always simultaneously pursued his hypotheses at fundamental levels, and sought novel translational opportunities to apply his scientific discoveries to improve the practice of cardiovascular medicine and patient outcomes. This record of consistent basic and translational research accomplishment and prowess, together with his impressive record of outstanding mentoring, clinical, and leadership abilities, establish Dr. Simon as an exemplar of the physician investigator.”


About University Hospitals
Founded in May 1866, University Hospitals serves the needs of patients through an integrated network of 18 hospitals, more than 40 outpatient health centers and primary care physician offices in 15 counties throughout Northeast Ohio. At the core of our $4 billion health system is University Hospitals Case Medical Center, ranked among America’s best hospitals by U.S. News & World Report. The primary affiliate of Case Western Reserve University School of Medicine, UH Case Medical Center is home to some of the most prestigious clinical and research programs in the nation, including cancer, pediatrics, women's health, orthopaedics, radiology, neuroscience, cardiology and cardiovascular surgery, digestive health, transplantation and genetics. Its main campus includes UH Rainbow Babies & Children's Hospital, ranked among the top children’s hospitals in the nation; UH MacDonald Women's Hospital, Ohio's only hospital for women; and UH Seidman Cancer Center, part of the NCI-designated Case Comprehensive Cancer Center at Case Western Reserve University. UH is the second largest employer in Northeast Ohio with 26,000 employees. For more information, go to

The American College of Cardiology is a 49,000-member medical society that is the professional home for the entire cardiovascular care team. The mission of the College is to transform cardiovascular care and to improve heart health. The ACC leads in the formation of health policy, standards and guidelines. The College operates national registries to measure and improve care, provides professional medical education, disseminates cardiovascular research and bestows credentials upon cardiovascular specialists who meet stringent qualifications. For more information, visit